Research
In systems biology, a cell or an aggregate of cells is thought to
comprise a system consisting of measurable components that interact with
each other. In general, systems biology can be thought to consist of three layers:
- Identification of components of a system.
- Identification of interactions between the components.
- Identification of systems level behavior of the system characterized by the components or their aggregates (sometimes referred to as modules).
At the moment our efforts focus mainly to identifying key components and their
interactions in cancers. Current projects include:
- Systems biology approach for analysis of transcriptional regulation:
Hox-gene circuits in cancer. Funded by the Academy of Finland SysBio-program.
- Mathematical analysis of signal transduction cascades
- Bioinformatic analysis of microarray data in breast and prostate cancer.
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