Marja-Leena Linne |
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Dr.Tech., Docent |
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Biography |
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Dr. Marja-Leena Linne is Senior researcher in the Department of Signal Processing at Tampere University of Technology and Coordinator of the INCF (International Neuroinformatics Coordination Facility) National Node of Finland. She is leading the Computational Neuroscience Research group at Tampere University of Technology. Dr. Linne received M.Sc. in electrical engineering from Tampere University of Technology, Dept. of Electrical Engineering, in 1993 and Ph.D. in signal processing and computational neuroscience from Tampere University of Technology, Dept. of Information Technology, in 2001. The Academy of Finland awarded her a Postdoctoral researcher position in 2002-2003 and an independent Academy Research fellow position in 2004-2009. Dr. Linne has visited several leading laboratories in her field in foreign universities, including Albany Medical College (USA), California Institute of Technology (USA), University of Antwerp (Belgium), and University of Pavia (Italy). Dr. Linne has altogether 17 years of research experience in biophysics, bioelectricity, and electrophysiology, 14 years of experience in computational neuroscience, and eight years of experience in computational systems biology. Dr. Linne has graduated three Ph.D. and eight M.Sc. theses as appointed supervisor by the faculty. She has been teaching courses ranging from Cellular Electrophysiology and Basics of Cell Biology to Digital and Signal Processing Project courses. Dr. Linne’s research contributions include both experimental and computational studies for understanding bioelectrical (electrophysiological) and biochemical phenomena in cells in vitro. She has also developed new computational algorithms and techniques, including stochastic approaches, for simulation of neuronal systems. In addition, she has done comparative evaluation of algorithms, tools, and computational models. In addition to computational and theoretical neurosciences, Dr. Linne has experience in using primary and secondary cell cultures (e.g. cerebellar granule cell and cortical cell cultures, SH-SY5Y neuroblastoma cell cultures, glial-neuronal co-cultures) and different electrophysiological recordings techniques (e.g. single-channel patch clamp, whole-cell patch clamp, two-electrode voltage clamp, and microelectrode arrays on cultured cells) in her research. She has obtained some training in molecular biology techniques as well. Dr. Linne’s recent work has focused on modeling the neuronal growth and activity for better understanding of the dynamics and structure-function relationship of neuronal networks in vitro. Dr. Linne is a co-principal investigator in the Centre of Excellence in Signal Processing appointed by Academy of Finland. |
