14.11.2006 Ulla Ruotsalainen, Tel. 358-(0)3-31154347 or 358-(0)40-7470327

 

PUBLICATIONS

 

Doctoral Thesis: Quantification and Data Analysis in Positron Emission Tomography: Organ Blood Flow, Graphical Analysis and Radiation Dosimetry. Tampere University of Technology: Publications 224. Tampere 1997.

 

1.Articles in international journals or compilations with referee practise

 

1990

 

1.Rinne JO, Laihinen A, Någren K, Bergman J, Solin O, Haaparanta M, Ruot­salainen U, Rinne UK. PET demonstrates different behaviour of striatal dopamine D1 and D2 receptors in early Parkinson’s disease. J Neurosci Res 27:494-499, 1990.

 

2. Rinne UK, Laihinen A, Rinne JO, Någren K, Bergman J, Ruotsalainen U. Positron emission totography (PET) demonstrates supersensitivity in the striatum of patients with early Parkinson’s disease. Movement Disorders 5:55-59,1990.

 

1991

 

3. Leskinen-Kallio S, Någren K, Lehikoinen P, Ruotsalainen U, Joensuu H. Uptake of (11C)-methionine in breast cancer studied by PET. Br J Cancer 64: 1121-1124, 1991.

 

4. Leskinen-Kallio S, Ruotsalainen U, Någren K, Teräs M, Joensuu H. Uptake of Carbon-11- methionine and FDG in non-Hodgkin’s lymphoma: A PET study. J Nucl Med 32: 1211-1218, 1991.

 

1992

 

5. Knuuti J, Nuutila P, Ruotsalainen U, Saraste M, Härkönen R, Ahonen A, Teräs M, Haaparanta M, Wegelius U, Haapanen A, Hartiala J, Voipio-Pulkki LM. Euglycemic hyperinsulinemic clamp and oral load in stimulating myocardial glucose utilization during positron emission tomography. J Nucl Med 33, 1255-1262, 1992.

 

6. Laihinen A, Rinne JO, Rinne UK, Haaparanta M, Ruotsalainen U, Bergman J, Solin O. FDOPA PET scanning in Parkinson’s disease after slective COMT inhibition with nitecapone (OR-462). Neurology 42:199-203, 1992.

 

7. Leskinen-Kallio S, Någren K, Lehikoinen P, Ruotsalainen U, Teräs M, Joensuu H. Carbon-11-methionine and PET is an effective method to image head and neck cancer. J Nucl Med 33(5):691-695, 1992.

 

8. Leskinen-Kallio S, Huovinen R, Någren K, Lehikoinen P, Ruotsalainen U, Teräs M, Joensuu H. Methods of (11C)methionine quantitation in cancer PET studies. J Comput Assist Tomogr 16:468-474, 1992.

 

9. Nuutila P, Koivisto VA, Knuuti J, Ruotsalainen U, Teräs M, Haaparanta M, Berg­man J, Solin O, Voipio-Pulkki LM, Wegelius U, Yki-Järvinen H. Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo. J Clin Invest 89:1767-1774, 1992.

 

10. Suhonen-Polvi H, Ruotsalainen U, Kero P, Korvenranta H, Bergman J, Haaparanta M, Simell O, Wegelius U. Functional development of the brain during the first months of life. A FDG positron emission tomography study. Fetal Diagn Ther 7:37-38, 1992.

 

1993

 

11. Huovinen R, Leskinen-Kallio S, Någren K, Lehikoinen P, Ruotsalainen U, Teräs M. Carbon-11 methionine and PET in evaluation of treatment response of breast cancer. Br J Cancer 67:787-791, 1993.

 

12. Knuuti J, Nuutila P, Ruotsalainen U, Teräs M, Saraste M, Härkönen R, Ahonen A, Wegelius U, Haapanen A, Bergman J, Haaparanta M, Voipio-Pulkki LM. The value of quantitative analysis of glucose utilization in detection of myocardial viability by PET. J Nucl Med 34:2068-2075, 1993.

 

13. Lindholm P, Minn H, Leskinen-Kallio S, Bergman J, Ruotsalainen U, Joensuu H. Influence of the blood glucose concentration on FDG uptake in cancer. J Nucl Med 34:1-6, 1993.

 

14. Lindholm P, Leskinen-Kallio S, Minn H, Bergman J, Haaparanta M, Lehikoinen P, Någren K, Ruotsalainen U, Teräs M, Joensuu H. Comparison of fluorine-18-deoxyglu­cose and carbon-11-methionine in head and neck cancer. J Nucl Med 34:115-123, 1993.

 

15. Minn H, Leskinen-Kallio S, Lindholm P, Bergman J, Ruotsalainen U, Teräs M, Haaparanta M. Quantification of FDG uptake in tumor: kinetic vs steady-state methods with reference to plasma insulin concentration. J Comput Assist Tomogr 17:115-123, 1993.

 

16. Nuutila P, Knuuti J, Ruotsalainen U, Koivisto VA, Eronen E, Teräs, Bergman J, Haaparanta M, Voipio-Pulkki LM, Viikari J, Rönnemaa T Wegelius U, Yki-Järvinen H. Insulin resistance in localized to skeletal but not heart muscle in Type I diabetes. Am J Physiol 264(Endocinol. Metab. 27):E756-E762, 1993.

 

17. Rinne JO, Hietala J, Ruotsalainen U, Någren K, Lehikoinen P, Laihinen A, Syvälahti E. Decrease in human striatal dopamine D2 receptor density with age: a PET study with (11C)raclopride. J Cereb Blood Flow Metab 13:310-315, 1993.

 

18. Rinne JO, Laihinen A, Rinne UK, Någren K, Bergman J, Ruotsalainen U. PET study on striatal dopamine D2 receptor changes during the progression of early Parkin­son’s disease. Movement Disorders 8: No 2:134-138, 1993.

 

19. Suhonen-Polvi H, Korvenranta H, Kero P, Ruotsalainen U, Simell O, Wegelius U. Repeated FDG-PET studies of the brain in infants with suspected hypoxic ischaemic brain injury. Eur J Nucl Med 20:759-765, 1993.

 

20. Voipio-Pulkki LM, Nuutila P, Knuuti J, Ruotsalainen U, Haaparanta M, Teräs M, Wegelius U, Koivisto VA. Heart and skeletal muscle glucose disposal in type 2 dia­betic patients as determined with positron emission tomography. J Nucl Med 34:2064-2067, 1993.

 

 

1994

 

21. Hietala J, Syvälahti E, Vuorio K, Någren K, Lehikoinen , Ruotsalainen U, Räkköläinen V, Lehtinen V, Wegelius U. Striatal dopamine D2 receptor characteristics in neuroleptic-naive schizophrenic patients studied with positron emission tomogra­phy. Arch Gen Psychiatry 51:116-123, 1994.

 

22. Hietala J, West C, Syvälahti E, Någren K, Lehikoinen P, Sonninen P, Ruotsalainen U. Striatal D2 receptor characteristics in patients with alcohol depence in vivo. Psy­chopharmacology 116:285-290, 1994.

 

23. Knuuti J, Yki-Järvinen H, Voipio-Pulkki LM, Mäki M, Ruotsalainen U, Wegelius U, Härkönen R, Teräs M, Bergman J, Hartiala J, Haaparanta M, Wegelius U, Nuutila P. Enchancement of myocardial glucose utilization by nicotinic acid derivative. J Nucl Med 35:989-998, 1994

 

24. Laihinen A, Rinne JO, Ruottinen H, Någren K, Lehikoinen P, Oikonen V, Ruot­salainen U, Rinne UK. PET Studies on dopamine D1 receptors in human brain with Carbon-11-SCH 39166 and Carbon-11-NNC 756. J Nucl Med 1994: 35:1916-1920.

 

25. Lapela M, Leskinen-Kallio S, Varpula M, Grenman S, Alanen K, Någren K, Lehikoinen P, Ruotsalainen U, Teräs M, Joensuu H. Imaging of uterine carcinoma with Carbon-11 methionine and PET. J Nucl Med; 35:1618-1623, 1994.

 

26. Lindholm P, Leskinen-Kallio S, Kirvelä O, Någren K, Lehikoinen P, Pulkki K, Peltola O, Ruotsalainen U, Teräs M, Joensuu H. Head and neck cancer: Effect of food ingestion on uptake of (11C)methionine. Radiology 190:863-867, 1994.

 

27. Minn H, Nuutila P, Lindholm P, Ruotsalainen U, Bergman J, Teräs M, Knuuti J. In vivo effects of insulin on tumor and skeletal muscle glucose metabolism in patients with lymphoma. Cancer 73:1490-1498, 1994.

 

28. Nuutila P, Knuuti J, Heinonen OJ, Ruotsalainen U, Teräs M, Bergman J, Solin O, Yki-Järvinen H, Voipio-Pulkki LM, Wegelius U, Koivisto VA. Different alterations in insulin stimulated glucose uptake in heart and skeletal muscle after physical training. J Clin Invest 93:2267-2274, 1994.

 

29. Nuutila P, Knuuti J, Raitakari M, Ruotsalainen U, Teräs M, Voipio-Pulkki Lm, Haaparanta M, Solin O, Wegelius U, Yki-Järvinen H. Effect of antiliposis on heart and skeletal muscle uptake in overnight fasted humans. Am J Physiol 267:E941-E946, 1994.

 

1995

 

30. Hietala J, Syvälahti E, Vuorio K, Räkköläinen V, Bergman J, Haaparanta M, Solin O, Kuoppamäki M, Ruotsalainen U, Salokangas R. Presynaptic dopamine function in striatum is increased in neuroleptic-naive first-episode schizophrenic patients. Lancet 346:1130-1131, 1995.

 

31. Laihinen A, Rinne JO, Ruottinen H, Någren K, Lehikoinen P, Oikonen V, Ruot­salainen U, Rinne UK. PET Studies on dopamine D1 receptors in the human brain with (11C)b-CIT in normal subjects and Parkinsonian patients. J Nucl Med 1995; 36:1263-1267.

 

32. Lapela M, Leskinen-Kallio S, Varpula M, Grenman S, Salmi T, Alanen K, Någren K, Lehikoinen P, Ruotsalainen U, Teräs M, Joensuu H. Metabolic imaging of ovarian tumors with Carbon-11-Methionine: a PET study. J Nucl Med 36:2196-2200, 1995.

 

33. Lapela M, Grenman R, Kurki T, Joensuu H, Leskinen S, Lindholm P, Haaparanta M, Ruotsalainen U, Minn H. FDG PET: Detection of recurrence in head and neck can­cer. Radiology 197:205-211, 1995.

 

34. Lapela M, Leskinen S, Minn H, Lindholm P, Klemi P, Söderström K-O, Bergman J, Haaparanta M, Ruotsalainen U, Solin O, Joensuu H. Increased glucose metabolism in untreated non-Hodgkin’s Lymphoma: a study with positron emission tomography and FDG. Blood 1995:3522-3527.

 

35. Lindholm P, Leskinen-Kallio S, Någren K, Lehikoinen P, Ruotsalainen U, Teräs M, Joensuu H. Positron emission tomography and Carbon-11-methionine in the imaging of malignant melanoma. J Nucl Med 1995:36:1806-1810.

 

36. Lindholm P, Leskinen-Kallio S, Grenman R, Lehikoinen P, Någren K, Teräs M, Ruotsalainen U, Joensuu H. Evaluation of response to radiotheraphy in head and neck tumors by positron emission tomography and (11C)methionine. Int J Radiat Oncol Phys 1995:32:787-794.

 

37. Nuutila P, Knuuti J, Mäki M, Laine H, Ruotsalainen U, Teräs M, Solin O, Yki-Jär­vinen H. Gender and insulin sensitivity. Diabetes 44:31-36,1995.

 

38. Nuutila P, Mäki M, Knuuti J, Laine H, Ruotsalainen U, Luotolahti M, Haaparanta M, Solin O, Jula A, Koivisto VA, Voipio-Pulkki LM, Yki-Järvinen H. Insulin action on heart and skeletal muscle uptake in essential hypertension. J Clin Invest 96:1003-1009, 1995.

 

39. Raitakari M, Knuuti J, Ruotsalainen U, Laine H, Mäkelä P, Teräs M, Sipilä H, Nis­kanen T, Raitakari O, Härkönen R, Wegelius U, Yki-järvinen H, Nuutila P. Insulin increases blood volume in human skeletal muscle. Am J Physiol 1995; 269:E1000-1005.

 

40. Rinne JO, Hublin C, Partinen M, Ruottinen H, Ruotsalainen U, Någren K, Lehikoinen P, Laihinen A. Positron emission tomography study of human narcolepsy: No increase in striatal dopamine D2 receptors. Neurology 45:1735-1738, 1995.

 

41. Rinne JO, Laihinen A, Någren K, Ruottinen H, Ruotsalainen U, Rinne UK. Ima­ging the monoamine transporter with (11C)-CIT and (11C)-CFT in early Parkinson’s disease. Synapse 21:97-103, 1995.

 

42. Rinne JO, Laihinen A, Ruottinen H, Ruotsalainen U, Någren K, Lehikoinen P, Oikonen V, Rinne UK. Increased density of dopamine D2 receptors in the putamen, but not the caudate nucleus in early Parkinson’s disease: a PET study with (11C)raclo­pride. Journal of the Neurological Sciences 132:156-161, 1995.

 

43. Ruottinen H, Rinne JO, Ruotsalainen U, Haaparanta M, Oikonen V, Bergman JR, Solin O, Laihinen A, Rinne UK. The effect of COMT inhibition with entacapone on striatal FDOPA utilization studied with PET in advanced Parkinson’s disease. J Neural Transm 10:91-106, 1995.

 

44. Suhonen-Polvi H, Salmi T, Korhonen T, Norvasuo-Heilä M, Ruotsalainen U, Riikonen R, Bergman J, Haaparanta M, Nuutila P, Valavaara R, Sonninen R, Wegelius U. Cerebral glucose utilization measured with positron emission tomography (PET) as an index for neurological functioning in long-term survivors of childhood acute lym­phoblastic leukemia. J Inter Haematol Neurol 2:63-71,1995.

 

45. Suhonen-Polvi H, Ruotsalainen U, Kinnala A, Bergman J, Haaparanta M, Teräs M, Mäkelä P, Solin O, Wegelius U. Positron emission tomography with 2-[18F]fluoro-2-deoxy-D-glucose in early infancy: simplified quantification methods for measuring cerebral glucose utilization. J Nucl Med 36:1249-1254, 1995.

 

1996

 

46. Kinnala A, Suhonen-Polvi H, Äärimaa T, Kero P, Korvenranta H, Ruotsalainen U, Bergman J, Haaparanta M, Solin O, Nuutila P, Wegelius U. Cerebral metabolic rate for glucose during the first six months of life: a FDG positron emission tomography study. Arch of Disease in Childhood 74:F153-F157, 1996.

 

47. Metsähonkala L, Äärimaa T, Sonninen P, Mikola H, Ruotsalainen U. CT, MRI and PET in a case of intractable epilepsy. Child’s Nerv Syst 1996; 12:421-424.

 

48. Mäki M, Luotolahti M, Nuutila P, Iida H, Voipio-Pulkki LM, Ruotsalainen U, Haa­paranta M, Slin O, Hartiala J, Härkönen R, Knuuti J. Glucose uptake in the chronically dysfunctioning but viable myocardium. Circulation 93: 1658-1666, 1996.

 

49. Nuutila P, Raitakari M, Laine H, Kirvelä O, Takala T, Utriainen T, Mäkimattila S, Pitkänen OP, Ruotsalainen U, Iida H, Knuuti J, Yki-Järvinen H. Role of blood flow in regulating insulin-stimulated glucose uptake in humans, studies using Bradykinin, [15O]Water, and FDG and positron emission tomography. J Clin Invest 7:1741-1747, 1996.

 

50. Raitakari M, Nuutila P, Ruotsalainen U, Teräs M, Iida H, Laine H, Mäkimattila S, Utriainen T, Oikonen V, Sipilä H, Haaparanta M, Solin O, Wegelius U, Knuuti J, Yki-Järvinen H. Evidence for dissosiation of the hemodynamic and metabolic effects of insulin in human skeletal muscle. Studies using (15O)H2O, FDG and positron emis­sion tomography. Diabetes 45:1471-1477, 1996.

 

51. Raitakari M, Nuutila P, Ruotsalainen U, Teräs M, Utriainen T, Mäkimattila S, Eronen E, Raitakari OT, Iida H, Knuuti J, Yki-Järvinen H. Relationship between limb and muscle blood flow in man. J Physiol 1996; 496:543-549.

 

52. Rinne JO, Hublin C, Partinen M, Ruottinen H, Någren K, Lehikoinen P, Ruot­salainen U, Laihinen A. Striatal dopamine D1 receptors in narcolepsy: A PET study with (11C)NNC 756. J Sleep Res 5:262-264, 1996.

 

53. Ruotsalainen U, Suhonen-Polvi H, Eronen E, Kinnala A, Bergman J, Haaparanta M, Teräs M, Solin O, Wegelius U. Estimated radiation dose to the newborn in FDG PET study. J Nucl Med 1996; 37:387-393.

 

1997

 

54. Alenius S, Ruotsalainen U. Bayesian image reconstruction for emission tomography based on median root prior. Eur J Nucl Med 1997:24:366-375.

 

55. Kinnala A, Nuutila P, Ruotsalainen U, Teräs M, Bergman J, Haaparanta M, Solin O, Korvenranta H, Äärimaa T, Wegelius U, Kero P, Suhonen-Polvi H. Cerebral meta­bolic rate for glucose after neonatal hypoglycaemia. Early Human Development 49:63-72, 1997.

 

56. Lamusuo S, Ruottinen H, Knuuti J, Härkönen R, Ruotsalainen U, Bergman J, Haa­paranta M, Solin O, Mervaala E, Nousiainen U, Jääskeläinen S, Ylinen A, Kälviäinen R, Rinne JK, Vapalahti M, Rinne JO. A comparison of FDG-PET, HMPAO-SPECT and 123I-iomatzenil-SPECT in localizing the epileptogenic cortex. J Neurosurgery and Psychiatry 63:743-748, 1997.

 

57. Leskinen S, Pulkki K, Knuuti J, Kirvelä O, Lehikoinen P, Någren K, Ruotsalainen U, Teräs M, Wegelius U, Salminen E. Transport of Carbon-11-methionine in enchan­ced by insulin. J Nucl Med 38:1967-1970, 1997.

 

58. Malminiemi K, Laine H, Knuuti J, Ruotsalainen U, Oikonen V, Haaparanta M, Nuutila P. Acute effects of celiprolol on muscle blood flow and insulin sensitivity. Studies using 15O-water, FDG and positron emission tomography. Eur J of Clinical Pharmacology 52:19-26, 1997.

 

59. Raitakari M, Nuutila P, Knuuti J, Raitakari OT, Laine H, Ruotsalainen U, Kirvelä O, Takala T, Iida H, Yki-Järvinen H. Effects of insulin on blood flow and volume in skeletal muscle of patients with insulin dependent diabetes mellitus. Diabetes 46:2017-2021, 1997.

 

60. Ruotsalainen U, Raitakari M, Nuutila P, Oikonen V, Sipilä H, Teräs M, Knuuti J, Bloomfield P, Iida H. Quantitative blood flow measurements of skeletal muscle using 15O-H2O and positron emission tomography. J Nucl Med 1997; 38:314-319.

 

61. Ruottinen H, Rinne JO, Oikonen V, Bergman J Haaparanta M, Solin O, Ruot­salainen U, Rinne UK. Striatal FDOPA accumulation after combined inhibition of per­iferal Catechol-O-Methyltransferase and Monoamine Oxidase Type B: differing response in relation to presynaptic dopaminenergic dysfunction. Synapse 27:336-346,1997.

 

62. Salonen I, Hietala J, Laihinen A, Lehikoinen P, Leino L, Någren K, Ruotsalainen U, Oikonen V, Tuokkola T, Näntö V. A PET study on the acute effect of ethanol on striatal D2 dopamine receptors with 11C-raclopride in healthy males. Human Psy­chopharmacology, 12: 145-152, 1997.

 

63. Utriainen T, Nuutila P, Takala T, Vicini P, Ruotsalainen U, Rönnemaa T, Tolvanen T, Raitakari M, Haaparanta M, Kirvelä O, Cobelli C, Yki-Järvinen H. Intact insulin stimulation of skeletal muscle blood flow, its heterogeneity and redistribution, but not of glucose uptake in non-insulin-dependent diabetes mellitus. J Clin Invest 1997; 100:777-785.

 

1998

 

64. Alenius S, Ruotsalainen U, Astola J. Using local median as the location of the prior distribution in iterative emission tomography image reconstruction. IEEE Transactions on Nuclear Science 45(6):3097-3105, 1998.

 

65. Laine H, Knuuti J, Ruotsalainen U, Utriainen T, Oikonen V, Raitakari M, Luoto­lahti M, Kirvelä O, Vicini P, Cobelli C, Nuutila P, Yki-Järvinen H. Preserved relative dispersion but blunted stimulation of mean flow, absolute dispersion and blood volume by insulin in skeletal muscle of patients with essential hypertension. Circulation 1998.

 

66. Laine H, Luotolahti M, Knuuti J, Raitakari M, Ruotsalainen U, Iida H, Kapanen J, Kirvelä O, Haaparanta M, Yki-Järvinen H, Nuutila P. Insulin resistance in essential hypertension is characterized by impaired insulin stimulation of blood flow in skeletal muscle. J Hypertension 16:211-219, 1998.

 

1999

 

67. Alenius S, Ruotsalainen U, Astola J. Attenuation correc­tion for PET using count-limited transmission images reconstructed with Median Root Prior. IEEE Transactions on Nuclear Science 46(3):646-651, 1999.

 

68. Hietala J, Någren K, Lehikoinen P, Ruotsalainen U, Syvälahti E. Measurement of striatal D2 dopamine receptor density and affinity with 11C-raclopride in vivo: A test-retest anal­ysis. J Cereb Blood Flow and Metabolism; 19(2):210-217, 1999.

 

69. Hietala J, Syvälahti E, Vilkman H, Vuorio K, Räkköläinen V, Bergman J, Haa­paranta M, Solin O, Kuoppamäki M, Eronen E, Ruotsalainen U, Salokangas R.K.R. Depressive symptoms and presynaptic dopamine function in neuroleptic-naïve schizo­phrenia. Schizophrenia research 35:41-50, 1999.

 

70. Katoh C, Ruotsalainen U, Laine H, Alenius S, Iida H, Nuutila P, Knuuti J. A new reconstruction method based on median root prior in quantification of myocardial blood flow and oxygen metabolism with PET. J Nucl Med 40(5):862-867, 1999.

 

71. Laine H, Katoh C, Luotolahti M, Yki-Järvinen H, Kantola I, Jula A, Takala T, Ruotsalainen U, Iida H, Haaparanta M, Nuutila P, Knuuti J.  Myocardial oxygen con­sumption is unchanged but efficiency is reduced in patients with essential hypertension and left ventricular hypertrophy. Circulation 100: 2425-2430, 1999.

 

72. Lamusuo S, Forss N, Ruottinen H, Bergman J, Mäkelä JP, Mervaala E, Solin O, Rinne JK, Ruotsalainen U, Ylinen A, Vapalahti M, Hari R, Rinne JO. [18F]FDG-PET and Whole-Scalp MEG Localization of Epileptonic Cortex. Epilepsia 40(7):921-930, 1999.

 

73. Nuutinen J, Minn H, Bergman J, Haaparanta M, Ruotsalainen U, Laine H, Knuuti J. Uncoupling of fatty acid and glucose metabolism in malignant lymphoma: a PET study. British Journal of Cancer 80(3/4):513-518, 1999.

 

74. Pitkänen O-P, Laine H, Kemppainen J, Eronen E, Alanen A, Raitakari M, Kirvelä O, Ruotsalainen U, Knuuti J, Koivisto VA, Nuutila P. Sodium nitropulside increases skeletal muscle blood flow, but does not change flow distribution or glucose uptake. Journal of Physiology London 521:729-737, 1999.

 

75. Suhonen-Polvi H, Varho T, Metsähonkala L, Haataja L, Ruotsalainen U, Haa­paranta M, Bergman J, Solin O, Äärimaa T, Holopainen I, Vainionpää L, Manner T, Jääskeläinen R, Renlund M, Sillanpää M, Aula P. Increased brain glucose utilization in Salla disease (Free Sialic Acid Storage Disorder). J Nucl Med 40:12-18, 1999.

 

76. Takala TO, Nuutila P, Katoh C, Luotolahti M, Bergman J, Mäki M, Oikonen V, Ruotsalainen U, Grönroos T, Haaparanta M, Kapanen J, Knuuti J. Myocardial blood flow, oxygen consumption and fatty acid uptake in endurance athletes during insulin stimulation. Am J Physiol (Endocrinology & Metab­olism) 276:E706-E711, 1999.

 

2000

 

77. Kalliokoski KK, Kemppainen J, Larmola K, Takala TO, Peltoniemi P, Oksanen A, Ruotsalainen U, Knuuti MJ, Cobelli C, Nuutila P. Muscle perfusion and perfusion het­erogeneity during exercise studied with positron emission tomography in humans. Eur J of Appl Physiology 83:395-401, 2000.

 

78. Kähkönen M, Metsähonkala L, Minn H, Utriainen T, Korhonen T, Norvansuo-Heila MK, Harila-Saari A, Äärimaa T, Suhonen-Polvi H, Ruotsalainen U, Solin O, Salmi TT. Cerebral glucose metabolism in survivors of childhood leukemia. Cancer 88(3):693-700, 2000.

 

79. Mykkänen J, Juhola M, Ruotsalainen U. Extracting VOIs from brain PET images. International Journal of Medical Informatics, 58-59:51-57, 2000.

 

80. Nuutila P, Peltoniemi P, Oikonen V, Larmola K, Kemppainen J, Takala T, Sipilä H, Oksanen A, Ruotsalainen U, Bolli GB, Yki-Järvinen H. Enhanced stimulation of glu­cose uptake by insulin increases exercise-stimulated glucose uptake in skeletal muscle in humans: Stdies using [O]O2, [F]fluoro-deoxy-glucose, and positron emission tomography. Diabetes 49:1084-1091, 2000.

 

2001

 

81. Mykkänen J, Tohka J, Ruotsalainen U. Automated delineation of brain structures with snakes in PET. In Molecular and Pharmacological Brain Imaging with Positron Emission Tomography. Academic Press: 39-43, 2001.

 

82. Oikonen VJ, Ruottinen HM, Ruotsalainen U. Special characteristics of 6-fluoro­dopa can cause biased estimates of dopa decarboxylation and dopamine loss rates. In Molecular and Pharmacological Brain Imaging with Positron Emission Tomography. Academic Press:187-191, 2001.

 

2002

 

83. Amari S-I, Beltrame F, Bjaalie J, Dalkara T, De Schutter E, Egan GF, Goddard NH, Gonzales C, Grillner S, Herz A, Hoffman K-P, Jääskeläinen IP, Koslow SH, Lee S-Y, Mathiessen L, Miller PL, da Silva FM, Novak M, Ravindranath V, Ruotsalainen U, Sebestra V, Subramaniam S, Toga AW, Usui S, van Pelt J, Vershure P, Willshaw D, Wrobel A, Yiyuan. Neuroinformatics: the integration of shared databases and tools towards integrative neuroscience. Journal for Integrative Neuroscience Vol.1, No.2: 117-128, 2002.

 

84. Hakala M, Karlsson H, Ruotsalainen U, Koponen S, Bergman J, Stenman H, Kelavuori JP, Aalto S, Kurki T, Niemi P. Severe somatization in women is associated with altered glucose metabolism. Psychological Medicine 32(8):1379-1385. 2002.

 

85. Alenius S, Ruotsalainen U. Generalization of Median Root Prior reconstruction. IEEE Transactions on Medical Imaging Vol.11: 1413-1420. 2002.

 

2003

 

86. Sohlberg A, Kuikka J, Ruotsalainen U. Pinhole single-photon emission tomography reconstruction based on median root prior. European Journal of Nuclear Medicine 30:217-221. 2003

 

87. Bettinardi V, Alenius S, Numminen P, Teräs M,Gilardi MC, Fazio F, Ruotsalainen U. Implementation and evaluation of an ordered subsets (OS) reconstruction algorithm for transmission (TR) positron emission tomography (PET) studies using median root prior (MRP) and inter-update median filtering. European Journal of Nuclear Medicine 30: 222-231. 2003.

 

88. Sohlberg A, Ruotsalainen U, Watabe H, Iida H, Kuikka J. Accelerated median root prior reconstruction in pinhole single-photon emission tomography. Phys Med Biol 48:1957-1969, 2003.

 

89. Eckersley P, Egan G, Amari S-I, Beltrame F, Bennet R, Bjaalie J, Dalkara T, De Schutter E, Gonzales C, Grillner S, Herz A, Hoffman K-P, Jääskeläinen IP, Koslow SH, Mira da Silva F, Novak M, Ravindranath V, Ruotsalainen U, Subramaniam S, Toga AW, Usui S, van Pelt J, Vershure P, Willshaw D, Wrobel A, Yiyuan T. Neuroscience data and tool sharing: a legal and policy framework for neuroinformatics. Neuroinformatics Journal, Vol 1: 149-166, 2003.

 

2004

 

90. Sohlberg A, Lensu S, Jolkkonen J, Tuomisto L, Ruotsalainen U, Kuikka JT. Improving the quality of small animal brain pinhole SPECT imaging by Bayesian reconstruction. European Journal of Nuclear Medicine 31:986-994, 2004 .

 

91. Tohka J, Kivimäki A, Reilhac A, Mykkänen J, Ruotsalainen U. Assessment of brain surface extraction from PET images using Monte Carlo simulator. IEEE Transactions on Nuclear Science, Vol. 51, No.5 pp: 2641-2648, 2004.

 

92. Happonen A, Ruotsalainen U. Three-dimensional alignment of scans in a dynamic PET study using sinusoidal trajectory signals of a sinogram. IEEE Transactions on Nuclear Science, Vol. 51, No 5 pp: 2620-2627, 2004.

 

2005

 

93. Sohlberg A, Jolkkonen J, Ruotsalainen, U, Kuikka JT. Imaging D2 receptors in quinolinic acid lesioned rat striatum with high resolution pinhole SPECT. Nuklear Medizin 44:N43, 2005.

 

94. Mykkänen J, Tohka J,  Luoma J, Ruotsalainen U. Automatic extraction of brain surface and mid-sagittal plane from PET images applying deformable models. Computer Methods and Programs in Biomedicine 79:1-17, 2005.

 

95. Juslin A, Reilhac A, Magadán-Méndez M, Albán E, Tohka J, Ruotsalainen U. Assessment of separation of functional components with ICA from cardiac perfusion phantom images for volume extraction with deformable surface models. Lecture Notes in Computer Science, Vol. 3540:338-347, 2005.

 

96. Happonen A, Ruotsalainen U. A Comparative study of angular extrapolation in sinogram and stackgram domains for limited angle tomography. Lecture Notes in Computer Science, Vol. 3540: 1047-1056, 2005.

 

2006

 

97. Tohka J, Wallius E, Hirvonen J, Hietala J, Ruotsalainen U. Automatic  extraction of caudate and putamen in [11C]raclopride PET using deformable surface models and normalized cuts. IEEE Transactions on Nuclear Science, 53(1):220-227, 2006.

 

98. Glotsos D, Tohka J, Soukka J, Soini J, Ruotsalainen U. Detection of outliers and robust estimation of bioaffinity assay fluorescence signals. IEEE Transactions on Information Engineering in Biomedicine, 10(4):733-739, 2006.

 

99. Krestyannikov E, Tohka J, Ruotsalainen U. Segmentation of dynamic emission tomography data in projection space. Lecture Notes in Computer Science, Vol. 4241:108-119, 2006.

 

100. Niemi JA, Ruotsalainen U, Saarinen A, Ruohonen K. Stochastic dynamic model for estimation of rate constants and their variances from noisy and heterogeneous PET measurements. Bulletin of Mathematical Biology (in press 2006).

 

101. Kostopoulos AE, Happonen A, Ruotsalainen U. Three-Dimensional alignment of objects in dynamic PET scans using filtered sinusoidal trajectories of sinogram. Nuclear Instruments and Methods in Physics Research Section A (In press, 2006)

 

102. Koikkalainen J, Nyman M, Hirvonen J, Lötjönen J, Hietala J, Ruotsalainen U. Shape Variability of the Human Striatum – Effects of Age and Gender. NeuroImage (in press 2006).

 

103. Juslin A, Lötjönen J, Nesterov SV, Kalliokoski K, Knuuti J, Ruotsalainen U. Alignment of 3D Dynamic H215O Cardiac PET Images with Mutual Information for Intervention Studies. J Nucl Cardiol (in press 2006).

 

4. Contribution in books and monographs

 

Rämö E, Toivio L, Ruotsalainen U. Digitaalisen kuvankäsittelyn menetelmät ja sovel­lutusalueet. Valtion teknillinen tutkimuskeskus (VTT) Tutkimuksia sarja 145, 1983.

 

Ruotsalainen U, Rämö E, Leppänen J, Heiska K. Digitaalinen kuvankäsittely lääketieteessä. Osa 1. Lääketieteellisen kuvantamisen tilanne ja kuvankäsittelyn mahdollisuu­det. Valtion teknillinen tutkimuskeskus (VTT) Tiedotteita sarja 375, 1984.

 

Rinne JO, Ruotsalainen U, Laihinen A. Positroniemissiotomografia. Luku 6, s. 71-78. Kirjassa Mieli ja aivot. Toim. Revonsuo A, Lang H, Aaltonen O. Kognitiivisen neuro­tieteen yksikkö, Turun yliopisto, Turku, ISBN 951-29-0852-2, Painosalama Oy, Turku.1996.

Ruotsalainen, U. PET-tutkimukset. In: Ahonen, A. et al. (eds.). Kliininen fysiologia ja isotooppilääketiede. Karisto Oy (Kustannus Oy Duodecim). s. 49-55. 2003.

 

5. Patents

 

Värri A, Koivuluoma M, Alametsä J, Ruotsalainen U. Laitteisto elintoimintojen mittaamiseksi. Hyödyllisyysmallijulkaisu /Utility Model Right FI 6295. National Board of Patents and Registration of Finland. 2004.

 

Ruotsalainen U, Happonen A, Alenius S. Patent application pending, 2004.